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ea0049ep1 | Adrenal cortex (to include Cushing's) | ECE2017

Confirmatory tests for diagnosis of primary aldosteronism among Chinese hypertensives

Jiang Minchun , Ma Dujuan , Lin Hailun , Lin Ying , Deng Yajuan , Tang Juying , Zhang Shaoling , Guo Ying

Objective: Primary aldosteronism (PA) has emerged as the most frequent form of secondary hypertension. For the diagnosis of PA, confirmatory testing is indispensable and different tests are recommended by guidelines, including captopril challenge test (CCT) and saline infusion test (SIT). However, there are sparse studies evaluating and comparing CCT and SIT in Chinese population. Hence, we investigate the diagnostic efficiency of CCT and SIT for PA in Chinese hypertensives in...

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ea0063p737 | Pituitary and Neuroendocrinology 2 | ECE2019

A multicentre, randomized, open-label, Phase IV study investigating management of pasireotide-associated hyperglycaemia with incretin-based therapy or insulin in patients with acromegaly or Cushing’s disease (CD)

Bolanowski Marek , Gu Feng , Feldt-Rasmussen Ulla , Zhang Shaoling , Yu Yerong , Witek Przemyslaw , Pedroncelli Alberto M , Nauwelaerts Heidi , Jabbour Nadine , Paul Michaela , Samson Susan

Background: Pasireotide has proven efficacy in acromegaly and CD, although pasireotide-associated hyperglycaemia occurs in some patients. This Phase IV, randomized, open-label study investigated optimal management of pasireotide-associated hyperglycaemia uncontrolled by metformin/oral antidiabetic therapy (OAD) [NCT02060383].Methods: Adults with acromegaly or CD were enrolled and treated with long-acting pasireotide 40 mg/28 days or subcutaneous pasireot...

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Endocrine Abstracts

Confirmatory tests for diagnosis of primary aldosteronism among Chinese hypertensives

A multicentre, randomized, open-label, Phase IV study investigating management of pasireotide-associated hyperglycaemia with incretin-based therapy or insulin in patients with acromegaly or Cushing’s disease (CD)

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